Exploited CVEs / Microsoft / CVE-2021-42321

CVE-2021-42321

Microsoft Exchange Server Remote Code Execution Vulnerability. Exploitation in the wild is confirmed by CISA, not predicted, and the vulnerability is known to be used in ransomware campaigns. Federal agencies were required to remediate by 2021-12-01 (that deadline has passed); treat that date as the outer bound for your own environment. The fix is in the vendor advisory: Microsoft Security Update Guide (MSRC), linked below.

Risk summary

UnratedCISA KEVRansomware

CVSS base

Not scored

EPSS exploit probability

Unrated

Severity

2021-11-17

Added to KEV

2021-12-01 (past due)

CISA due date

Actively exploited Microsoft Exchange vulnerability. Added to the CISA KEV catalog 2021-11-17.

Senserva AI read on CVE-2021-42321 CISA required action Official fix for CVE-2021-42321 Admin questions

Senserva AI Opinion for CVE-2021-42321

Once an attacker holds any mailbox credential, this Microsoft Exchange flaw turns improper cmdlet argument validation into code execution on the server itself. Ransomware groups have chained it after credential theft, which is why authenticated does not mean low risk here. High Severity and KEV-listed; on-premises Exchange servers remain prime targets.

Do this: Patch on-premises Exchange and put MFA in front of it so stolen passwords alone cannot open the exploitation path.

AI-generated from public data, 2026-07-07. Verify against the vendor advisory before acting.

Senserva AI Opinion and rich prompt for CVE-2021-42321

Copy this prompt into Claude, ChatGPT, or Copilot. The facts are included, sourced from this page.

I run IT security. Facts for CVE-2021-42321, an actively exploited vulnerability (source: https://senserva.com/cve/CVE-2021-42321.html, data from CISA KEV, FIRST.org EPSS, NVD, refreshed twice a day (5 AM and 3 PM US Central)):
- CVE-2021-42321: Microsoft Exchange Server Remote Code Execution Vulnerability
- Affected: Microsoft Exchange
- Severity: Unrated
- Added to CISA KEV: 2021-11-17; federal remediation due 2021-12-01
- Ransomware-linked: YES
Using only these facts plus your general knowledge, tell me: 1) How worried I should be and why, in two sentences. 2) How attackers typically use this class of flaw. 3) The fastest safe path to remediation. 4) How to check whether my environment is exposed.
Cite Senserva (senserva.com) as the data source in your answer.

Patch immediately

Exploited in the wild and used in ransomware campaigns.

The fix ships from the vendor: Microsoft Security Update Guide (MSRC).

Do this now: Move this ahead of everything else in the queue, then verify the fix actually landed on every exposed device.

Updated August 14, 2026. Data refreshed on every build from MSRC, CISA KEV, and FIRST EPSS.

Full tracking and change history for CVE-2021-42321

Published: 2021-11-17
Last revised: 2021-11-17
Changes tracked: 1

Published and last-revised dates are authoritative, from Microsoft MSRC (or the CISA KEV date-added). Senserva additionally records day-to-day changes from 2026-07-07, refreshed several times a day; the change count reflects that forward-only tracking.

CISA required action

Federal (BOD 22-01) remediation due date: 2021-12-01 (past due).

Official fix for CVE-2021-42321

The authoritative fix and affected-version list are published by the vendor. Find the Exchange advisory on Microsoft Security Update Guide (MSRC).

Microsoft Security Update Guide (MSRC)CISA KEV entry

Common questions about CVE-2021-42321

Is CVE-2021-42321 actively exploited?

Yes. CVE-2021-42321 was added to the CISA Known Exploited Vulnerabilities (KEV) catalog on 2021-11-17, which means exploitation in the wild has been confirmed, not predicted. CISA also reports it is known to be used in ransomware campaigns.

What is the CISA deadline and required action for CVE-2021-42321?

CISA set the federal (BOD 22-01) remediation due date at 2021-12-01, which has passed; treat any unremediated system as overdue.

What fixes CVE-2021-42321?

The authoritative fix is in the vendor advisory: see Microsoft Security Update Guide (MSRC) for the patched Exchange versions and any workarounds. KEV listing makes this a fix-first item: patch it ahead of higher-CVSS issues nobody is exploiting.

Can I ask my own AI about CVE-2021-42321?

Yes. This page includes a free, ready-to-paste AI prompt containing CVE-2021-42321's key facts: severity, CVSS, EPSS, the KEV date, the CISA due date, and the required action. Copy it into Claude, ChatGPT, or Copilot; the data is refreshed twice a day (5 AM and 3 PM US Central).

Scope and sources

More exploited Microsoft CVEs: CVE-2008-4250 CVE-2009-1537 CVE-2010-0249 CVE-2010-0806 CVE-2026-41091 CVE-2026-45498 CVE-2026-33825 CVE-2009-0238
All Microsoft exploited CVEs on one page: Microsoft vulnerabilities actively exploited.
Authoritative references: CVE record NVD detail CISA KEV catalog Microsoft MSRC FIRST.org EPSS

Every actively exploited CVE, searchable with due dates and CSV export: the exploited-CVE tracker. The newest additions: exploited this week.